NAD⁺ 500MG

描述

Core Features
$\ge 98\%$ Enzymatic Activity Grade Purity: This product is purified using a combination of precision biological fermentation and ion-exchange chromatography. Compared to lower-grade alternatives, our 500mg bulk format features strictly controlled moisture and residual solvent levels, ensuring an absolute $\beta$-conformation purity of $\ge 98\%$. This guarantees highly stable reaction rates in kinetic assays involving NAD⁺-dependent enzymes (such as PARPs, CD38, and Sirtuins) and eliminates metabolic background noise.
Optimized Redox Stability: This product represents the oxidized form of NAD⁺ and exhibits exceptional chemical stability within specific pH ranges. The 500mg format is specifically optimized for long-term research projects; processed via vacuum freeze-drying, the product appears as a loose, pure-white crystalline powder with low hygroscopicity, ensuring the molecular structure remains resistant to hydrolytic degradation caused by ambient humidity during repeated sampling.
Gold Standard Substrate for Mitochondrial and Aging Research: As an essential electron carrier in the cellular electron transport chain (ETC), this product is widely used to study mitochondrial oxidative phosphorylation dynamics. Its high-concentration formulation is ideal for preparing concentrated stock solutions, supporting research workflows ranging from in vitro single-cell cultures to in vivo administration in complex animal models.

🛠️ Technical Specifications & Physical Parameters
Product Specification: 500 mg / Screw-Cap Shielding Vial
Chemical Name: $\beta$-Nicotinamide Adenine Dinucleotide ($\beta$-NAD⁺)
Molecular Formula: $\text{C}_{21}\text{H}_{27}\text{N}_{7}\text{O}_{14}\text{P}_{2}$
Appearance: White to off-white powder; highly hygroscopic.
Solubility: Highly soluble in water (>50 mg/mL), forming a clear, transparent solution.
Validation: Accompanied by original manufacturer NMR structural identification and HPLC purity reports; supports batch-to-batch data consistency verification.

❄️ Storage & Handling Protocols
Storage Policy: Upon receipt, store immediately at $-20^\circ\text{C}$ in a dry, dark environment (short-term storage at $4^\circ\text{C}$ is permissible). NAD⁺ is extremely sensitive to temperature and humidity; ensure the cap is tightly sealed to prevent deliquescence and discoloration caused by air exposure.
Reconstitution Advice: Reconstitute using sterile ultrapure or deionized water filtered through a 0.22 µm membrane. As NAD⁺ exhibits poor stability in solution (especially at higher pH levels), it is strongly recommended to aliquot the solution immediately after reconstitution and store at $-80^\circ\text{C}$. Repeated freeze-thaw cycles are strictly prohibited.

📝 Research Compliance & Disclaimer
⚠️ Strictly For Research Use Only: This product (NAD⁺ 500 mg) is a biochemical reagent intended for advanced life science research. In strict adherence to global compliance standards, this product is intended solely for academic research within university laboratories, research institutes, or corporate R&D centers (e.g., analysis of mitochondrial metabolic pathways, *in vitro* enzymology experiments). Any non-compliant use—such as clinical injection in humans, oral supplementation, or direct consumption as a health supplement—is strictly prohibited. This platform rigorously enforces the verification of “End-Use Declarations.”